In his Autobiography, Charles Willson Peale recorded painting Dr. Williams and his wife in Accomack County. The location and subject are unknown.
Reference: “During the stay of Peale in Accomack he painted the portraits of Doctr. Williams & Lady and 2 or 3 other Portraits, and at a leisure time he painted a piece from a print taken from a picture of Sir Joshua Reynolds.” in Peale’s Autobiography
See: Peale’s Autobiography, in Lillian Miller, ed., Selected Papers of Charles Willson Peale and his Family, V (1983): 25.